Insulin Resistance of the Brain (T3DM) and Our New Webinar Pilot

Insulin Resistance of the Brain (T3DM) and Our New Webinar Pilot


Okay, I’m gonna go ahead hopefully this
is working. I’m hearing from Loretta and Kimba too that it’s working so here we go.
Tonight, we’ve got several items I’d like to cover and I will… first of all, I do
this thing has me do a share… hold on. Let me find that share on here.
You hopefully, you can see that now. It’s the
YouTube live event for September 11 of 2019. I’ve got several things I’d like to
cover the first is 36 holes in the roof or another way of looking at it is IR of
the brain, insulin resistance, or diabetes of the brain. After we cover that, I’ll give you an update on a membership page pilot that we’re doing. A couple of
reminders. The LA CIMT event September 28th to find that you can go to CardioRisk.US/HealthyLife. When I did that video on it introducing it last
week, I gave you the wrong link. I gave you CardioRisk.US/Ford. All
that link will do is get you registered and they’ll send you an email whenever
they have whenever we have an event whether no matter where it is in the
country. The first event is scheduled as September 28th in Anaheim LA, and it’s on. To register and get your get your time to get the CIMT, go to
CardioRisk.US/HealthyLife. The Louisville event, just a quick
reminder on that, November 8th and 9th and you can find that at our website
prevmedheartrisk.com. The last thing I’ll cover is a webinar
pilot. Again, in this constant quest to try to get better access and lower costs
with high quality for folks to be able to get their own information regarding
“Do I have insulin resistance,” “Do I have cardiovascular inflammation,”
“Do I have plaque.” So 36 holes in the roof, now that’s a quote that comes from Dale
Bredesen. You may… some of you I’m sure have read it, “The End of Alzheimer’s.”
He gets a little bit deep in detail in terms of looking at just about every lab
plus the kitchen sink but there’s a lot of very very good information. I was in
the first well I’ll tell you about that in just a minute.
What is “36 holes in the roof” mean? Well tell you about that in just a
minute as well. Why don’t we call it insulin resistance or diabetes
of the brain. 80% of folks that have Alzheimer’s are known insulin
resistant or diabetic. The “36 holes in the roof” comes from a quote in the book.
There are at least 36 mechanisms contributing to Alzheimer’s disease so
fixing one has little chance for success. Fixing just one… the laboratory results
reveal the sizes of each hole for each person. Now
it so this is like the same thing with heart attacks and strokes.
You’re much better off preventing this than trying to get a cure. Now there’s a
couple of things that are helpful to remember about prevention and mild
cognitive impairment. Here’s the continuum. You start off with preclinical:
you’re getting some insulin resistance, you’re getting some impact on the brain
itself but not enough to have any symptoms. Then you go into what’s called
mild cognitive impairment or SCI (subjective cognitive impairment). The
typical thing you’ll hear from someone with SCI is you know “I keep telling
myself I’m not remembering names” as well as “I used to…” or “I’ve always been really
good at math and I’m just not able to click on some of the math the way I used
to.” I asked my friend and he said I’m crazy. He said, “I’m just as sure I’m
sharper than others in this area and I’m just as sharp as the next guy.” Here’s the
bad news, and you could ask your spouse. I think if I asked my wife, she would tell
me I’m, huh, you know you know spouses are gonna tell you they’re gonna see
it hope a whole different perspective so maybe as somebody who’s not quite as
emotionally connected. Here’s the thing. If your typical story for someone with
mild cognitive impairment or SCI (subjective cognitive impairment) is that
they’re right they are losing some mental quickness, some mental agility. And
again they’re the first one to notice it. Once you get to full-blown dementia,
again that’s as we talked before, there’s just there’s 36 holes in the roof. It’s
very difficult to start patching every one of those holes dealing with you know
there’s a perception about fungus and mold and a bunch of other stuff. We don’t
focus on that. We don’t. We do provide… we have provided a lot of services in this Alzheimer’s area but we’re focusing now mostly own subjective cognitive
impairment and insulin resistance. So just speaking about insulin resistance
in the overlap, I started to mention that I was in the first training class that
Bredesen had for physicians and providers to get into the network to
start providing this care. He came up to me after the event and he said, “What
did you think?” and I had to say, “Look, I was a little bit surprised that there
was actually so little information on insulin resistance.” And you know I was
giving what I considered to be a gross underestimate. I said, “Isn’t it at least
50% of the cause related to IR?” And he said… he looked at me kind of funny and
he said, “Well, I think it’s 100% related to insulin resistance.
80% are known insulin resistance. The rest are what we call ‘CNS’
insulin resistance. In other words, central nervous system or insulin resistance of
the brain. Now my response at that point was, yeah, are they also had had insulin
resistance in their body, but you’re just… but people are just measuring it, looking
at hemoglobin A1c or fasting glucose. Again, they’re missing a huge portion of
this problem. One other distinction to be aware of as we consider this is that
insulin in and of itself has a totally separate function within the brain and
it has to do with memory. So again, there’s a lot of dots to connect and to
be very frank in terms of the full science of Alzheimer’s, we haven’t
connected all the dots. We spend.. what… two or three trillion
or is it a year. I don’t know. Somebody check my facts on that. It’s a huge
amount of money trying to get deeper in terms of understanding Alzheimer’s. They focused a lot on amyloid beta, and some of those other biomarkers. Bottom
line is they haven’t developed a cure but it’s pretty clear that reversing
insulin resistance is a major preventive measure. Now this is an article from
Nature magazine. You don’t really get better than Nature magazine in terms of
hard science, and more and more articles are appearing labeling dementia,
Alzheimer’s as “type 3 diabetes.” Now this gets into a lot of the detail in
terms of some really geeky biomarkers linking to insulin resistance and
diabetes. We’re not going to go there tonight but again just to give you some
of the science or a brief 50,000 foot look at some of the science linking the
two. Now a couple of comments about how a couple of measurement components. You may
have heard of the MoCA before. MoCA stands for the Montreal Cognitive
Assessment. It’s one of the key tools that you use. It’s like one of the two
major tools you use in terms of cognitive impairment. You may have
remember last year the president. The story came out that maybe he requested
one of those, I’m not sure. But he had a MoCA, he had a cognitive agility test,
and they said he scored very well. I’m not gonna make any comments. Obviously, I
could make a lot of comments but this is not… this is a topic on science. It’s not
political satire. So Montreal Cognitive Assessment. What does it look for?
Short-term memory, executive function, orientation, clock
attention span, language, ability to abstract, and animal naming. So some
memory type of things. Now this is a highly standardized test. You have to get
certification in order to give a valid score. Janice, my wife, Dr.
Derrickson, does have… a one of the few people I know that does have
certification and training in providing this test and this part of what we
have services we’ve provided in the past for people with cognitive impairment. Now
one of the other major assessment item unique to cognitive
impairment has to do with hippocampal volume. The hippocampus is the part of
the brain that literally connects the dots. It provides the connection between
multiple thought centers. And so if you’re going to have a problem with
memory and connecting the dots, it’s likely to go through the hippocampus. Now
if you look at this, you already may have seen it, the hippocampus of a normal
control is very very different from the hippocampus of someone with Alzheimer’s.
So again, that’s another way you can take a look and start getting a little bit
better assessment of just what sort of equipment capacity you have up there. So
that’s a little bit about type 3 diabetes, insulin resistance of the brain,
Alzheimer’s cognitive decline. So I wanted to talk for a few minutes about a
pilot that we have going on. You can go see that now. I believe it’s a membership
page. Basically what we’re doing is we’re putting all of our digital content on
one page. So for those of you that have bought one of the courses, you can go in
and see the course here. If you haven’t bought a course but you’re
interested, you can get free previews of the courses. It also… will also be adding
a lot of free infographics. I just worked on editing
some of those today. They still have some need for edits. And as you can
tell, we’re growing fast in some areas that we haven’t tended to grow before in
terms of these digital products. They’re going to be a little bit rusty, a little
bit rough, until we… not so polished… until we get up and rolling. So please be
patient with us when you see a need for edits. But the new membership page is a
great way to start figuring out how to access our stuff. How do you get there? If
you go to the web page, it’s prevmedheartrisk.com, you’ll see a new button.
Click on membership login right there. That’ll take you to a place where you
create your free account and you just give your email, free account, password,
and there you go. A couple of quick reminders. As I mentioned with the
November 8th and 9th coming up for Louisville the event, you can get
your CIMT, all of your labs, and spend two days. More of an intense
boot camp type of environment, talking about how to interpret these labs, how to
interpret the CIMT, getting a report from a radiologist on these
interpretations. There will be one-on-one meetings with me. Many at the meeting and
some after the meeting. We did put a special in there for this is
this is the country. Horse-racing, liquor, and I can’t remember
what the other vice was. But people that have an interest,
we bought some a free Evan… Evan Williams distillery tour. Why we would do that? I don’t know, but if you have an interest, you don’t have to drink any of
the Bourbon. It’s sort of like the Disney of distilleries. It’s set up to
help you understand the history of this region. CardioRisk.US/HealthyLife I mentioned
that earlier. On September 28th, David Meinz is going to be giving a half-day
event in Anaheim. The registration is 2:45 that will cover the CIMT and the
reading. Also a half-day of discussion about what we do. Inflammation, insulin
resistance, your CIMT. And we’re gonna try to set it up to where Todd and I can
attend remotely. Whether we’re able to get that to work or not, it’s hard to
predict at this point. Again, we got a lot of things going on. Now the
last thing I wanted to make you aware of is our webinar series and this came up…
I’m not sure… I think it may have been Bart Robinson who asked about the
webinar. I mentioned that a couple of weeks ago in one of the live events and
this all started when one of our guys mistakenly published an old video that
Jon Lorscheider had done. It had to do with how to get labs on your own, and it
mentioned getting an inflammation panel from Quest. Several people latched on to
that gave Quest a call, and it’s outdated. Quest has not given individual access to
the inflammation panel anymore, but they still are giving it through us. So as the
discussions have continued to happen on that, I started to think… you know what… I
could… we have a contract with Quest and I could provide access to the
inflammation panel and the insulin survey through our contracts. So
that’s what we’re planning to do and then set up a series to go over… the
series of webinars to go over the results. So here’s what that is. The goal
is to provide actual measurement and interpretation of labs and imaging to
folks. Again, better access, lower costs to you, and high quality… continued high
quality so the registers… registrants would access their individual labs and
imaging results. That then attend a webinar to talk
about interpretation. The target time for these webinars would be 45 minutes. The
topic would be… the first one would be an intro to describe how the process works.
The second one would be a summary then we can get deeper in follow-ups with one
on plaque, one on insulin resistance and diabetes, then one on cardiovascular
inflammation. So what’s the process? Sign up for the webinar if you want to get
labs or lab orders then you contact [email protected] Contact Joseph or Michelle then you can get your inflammation panel, OGTT
with insulin or the calcium score. We talked about setting up the CIMT. That
takes a little time and we’re just not ready to do that in volume at this
point. So then you get those, you obtain the results, and then you attend the
webinar. You can obviously attend the webinar without those results, and you
can obviously attend the webinar before you get the results and after. What are
the times and dates? That we plan to set those up. We don’t know yet. Cliede’s gonna
send out a a survey and right now we’re planning on
starting Tuesdays 11:00 Eastern Time. Now I know we’re a 447 degrees west, that’s
that’s pretty tough for Alaska, Tom, and Laura Dell, and Ham. I know that that’s… I
would guess… that’s gonna be like 11:00 a.m. or something. I mean loving p.m.
maybe so it may be tough for the Australians as well. But again, sign up,
get the set up with the membership page, and we’ll start getting the surveys
out, and we will adjust as we need. Well what’s the price for this? If that’s to
be done, that ought to be decided. We’re working on that right now. Again, it’s
going to be much less than our intensive one-on-one, doing the whole one
thing one-on-one with me. The first free for the webinar itself would be are the
first 10 for the webinar itself will be free as a pilot. The lab costs will be to
be decided as well. Would cover other topics? Yeah, if it’s successful, we
plan to open it up. Isn’t this actually practicing medicine doing the
webinars? Not really. Until I will not be talking about anybody individual results,
unless the individual brings it up. If the individual brings up a question
about a specific result, we will be able to discuss that on the webinar. Orders
and individual reports… is getting more closer to practicing medicine. One of the
things we have to do is get your demographics and set you up as a patient in our EMR (electronic medical record) in order to provide those lab
orders. So for the lab orders… the lab orders, and if you get what we call cash
labs, just pay us. That will actually be more expensive than the webinar itself.
Again we’re working on pricing and access. We’ll keep you posted on that.
How will you be scheduled, how will be notified, videos, routine schedule.
Like you know, same time, same timeslot each week.
Facebook, Twitter, etc. How long for each topic? Again, the target 45 minutes for
each webinar with about 20 minutes, maybe 30 of me talking about content, and then
the rest of it set up for QA. Will there be speaking of which will
there be QA? Yes, there will be. I believe that is the end of the slideshow and I
hope you guys have been able to see this. Let me go back and ah let me see I hope this doesn’t so live on streaming service hopefully.
Oh well did I lose everybody. I don’t know. Okay, I’m gonna read off some
questions here. Oh there’s been a lot of activity. I see it.
Thumbs up. Yes I do. Hi doc oh my own sit key um Mr. Sadiki. How are you? Hello Dr.
Brewer. Why don’t my cardiologist and GP know any of this? Hmm.
I have to be careful what I say about that. IR is not even a part of their
vocabulary. Thanks for all the info. Thank you for the comment and you know here’s
the thing. The bottom line is if you’ve got 20 or 50 patients in your waiting
room who have who need a stent or they’ve got full-blown diabetes you
tend to just sort of pass quickly through somebody that may have much
lower levels. But the problem is it’s the lower levels, it’s that 20 years of
insulin resistance that creates the the risk, the plaque, the inflammation.
Adam Scott and let me just ask you this guys please let me know if you can still
see and hear me. I’m going to cover a few questions here. I think we had one
from Adam Scott. In your opinion, could you increase attention span through your
diet like foods high in tyrosine or something. Well you know the biggest
thing actually I just worked on my cognitive decline deck this morning and
there’s a lot of things out there. If you read Dale Bredesen’s book, he talks about
ashwagandha, any of the things that impact insulin resistance like cinnamon
berberine. All of those. There’s one
phosphatidylcholine is considered to be “brain food.” The reality is that all
of those do appear to have some impact. Here’s the thing. Though the major
driving force under all of this is that twenty years of very mild insulin
resistance picking away at your brain, just the way it picks away at the arteries the intima, the internal lining of the arteries. So the major focus is to
to manage that insulin resistance. There’s nothing more important to
managing that insulin resistance than diet. So number one, if you have insulin
resistance, don’t eat carbs if you can’t metabolize carbs, don’t eat
them. Number two, keeping your BMI at a good level. For
most of us, that’s in the low 20s. If you’re Arnold Schwarzenegger and you’re
at peak level I mean when he was at peak and won Mr. Olympia, he was actually at a
BMI of 30. Most of us don’t have that kind of muscle mass and that kind of fat
mass. The goal is to maximize muscle mass and decrease fat mass because muscle has
actually an insulin-like function, pulling blood sugar out of the blood and into the muscle. And fats have an inflammatory function. I’m
a guy here that… I may have to redo the the video… I did recently on the secret
life of fat cells but because of some sound tech issues but the bottom line is
we used to think fat was just a storage cell. Not at all. It is an endocrine cell
and it creates inflammation. It also creates insulin resistance. So Loretta
Dillingham. Who or where does an X-ray of the hippocampus get done. I don’t know
about Australia. I do know in the U.S. most places that have
especially a free-standing radiology unit with an M
most of those do have some access to the hippocampal volume study. Kelly Clover
answered a siddqi mainstream doctors are beholden to treatment guidelines which
have little to do with reality but it enriches powerful special interests
including big pharma. It’s a good point Kelly. I was involved when I was at
Hopkins I actually we had a contract. My residence actually developed the first
set of literature reviews the understanding of the science that the
first standards of preventive medicine the American College of Preventive
Medicine were written on standards committees are just like any other human
event. They are political. They have a human political involvement, and here’s
when you think about it this way you can understand why it still takes at least
15 years usually to get new developments from science into medical standards and
that is you’d pick the the experts in an area and those experts usually have to
admit that either their competitors sitting across the table or somebody
who’s not even in the room discovered something that they think they should
have discovered and they’ve got to acknowledge that it’s important and true.
So you know you got some big egos sitting around standards table or yeah
sitting around standards tables and it’s a slow human process. Most of these
things are changing but you have to be patient. Neil Higgins. Pardon me just a
second. Neil Higgins. This is not soda by the way,
no sugar in this. This is a sparkling water.
Neil Higgins. My cardiologist said a heart healthy diet would be a good idea
put me on Crestor and beta blockers I dropped all crappy carbs my CRP
c-reactive protein is now the lowest it’s been since 2012 when I was
diagnosed with PMR. Oh very good congratulations to you. It says we’ve got what of several dozen
concurrent viewers and hopefully we were still broadcasting so I’ll continue. Adam
Scott. Anyone know if he answers questions from this live chat. Adam, yes, I
do if I can wade through this confusing technology. See a live chat question like
this one and answer it. I certainly will. James Canter. Neal Higgins. What does PMR
stand for? Neil Higgins that morphed into rheumatoid arthritis this June had a CIC
over mm so Neal thank you for sharing that the others it’s a really really
good point Neal the others don’t Owen PMR what you meant polymyalgia
rheumatica. So here’s the thing. Most of us know most people know that diabetes
sets you up for a heart attack and stroke and inflammation. Very few people
know that the inflammatory diseases especially rheumatoid arthritis
polymyalgia rheumatica PMR lupus a lot several of the inflammatory diseases
create just as much risk for heart attack and stroke as diabetes for the
individual person it’s just the the inflammatory ologists now somebody else
asked I think Siddqi asked why don’t my
regular docs know this. Actually if you talk to your neurologist and your
rheumatologist and you’re especially rheumatologist and
dermatologists both tend to know a lot more about the cardiovascular
inflammation side because they deal with inflammatory diseases all the time. The
endocrinologists sometimes no but the problem with endocrinologist is they’re
in the same position that your primary care doc or your cardiologists are.
They’ve got a roomful of 50 full-blown diabetics and really don’t take the time
to focus on the more subtle challenges like we’re working on and what you have
to work on if you’re going to prevent these issues
okay sixty I hope that got the I hope that gave you the reply you were
searching for yes Adam Dr. B will canvas these questions answer what he can
Neil Higgins I lost 28 pounds since my CIC score off all sugars and flours etc
you know Neil losing 30 pounds is a life-changing event and I’ve got now
since most of my patients are coming in through the YouTube channel. It so… it’s
like over half of them have already lost 30 pounds before they come in to see me.
You know my obvious first reaction as well you may have just saved two or
three decades of healthy life. Oh what can I do for you now and the answer is
always the same. Yep I’m obviously really focused on this I want to get healthy I
know I’ve done a whole lot I know I’ve done most of the hard part but I want to
dial it in further and you can always dial it in further so that’s that’s what
I’m ending up doing these days. I’m spending actually less time talking
about inflammation 101 which I used to a couple of years ago and much more time
talking about the subtleties and it’s the blessings of the YouTube channel.
The folks that already come to me knowing a lot more than folks used to in
the past. Neil Higgins cardiologist and
rheumatologist haven’t even mentioned if I might be IR yeah the rheumatologist
and dermatologists do understand inflammation but they still don’t
understand subtle IR – well yeah most of them don’t
some of them do but the vast majority don’t. James Cantor Neil Higgins are
you over 65 well Neil half answer that David Wyman hi Doc love your work you
are a true pioneer. Well thank you very much I will I will say I will say thank
you again I’ll have to say that. When you tell me that it reminds me of the old
adage that pioneers get arrows and into facedown in the dust and the
settlers I forgot how it goes but sometimes I feel like yeah I’m getting
all the errors from the pioneer roll to the de Lorette Dillingham no
still here okay Neal Higgins 59 lifelong athlete ever cyclist asymptomatic for
heart disease. Good for you. 147 Degrees West there you are still
seeing here you Joey Boombots no I’m here IR interventional radiology no
insulin resistance IR in pardon pardon me I try to get away from acronym
ease but especially with IR. I start using that word insulin resistance. Neil
Higgins part of the problem is our so-called Free Canadian healthcare
system. Neil my brother lives in Canada there’s actually some really good
components to that Canadian healthcare system. One of them is you in Canada they
get Livalo but have a statin for about a tenth of the price that it costs us
here in the US. Peter Lane New Zealand loud and clear
good to good to hear from you Peter Richard lined LA it’s reported that it
protects the function of endothelial cells after a meal.
I’m not sure Oh gamma tocopherol okay sit keep thanks Dr. Brewers it keep it
yes thank you. Bart Robinson tuned in and got my full attention. Thank You Bart. I
hope you were the guy that had the questions about the webinar pilot and if
you weren’t I’m sorry but I hope you’re interested in it. Anyway, again, hopefully
a big increase in access, big improvement in cost.
Mr. White Tulley question can you talk about the sugar buster supplement you
posted yesterday. Okay Gymnema. I first heard of Gymnema a few years ago.
It’s a Gymnema, it’s dry. Usually you’ll get it as a dried powder. It’s a… I
think isn’t that the one that’s the cow plant… Cow Plant… anyhow what you get
it’s something that’s been used for over a thousand years in Ayurvedic medicine.
What the reason it’s called the sugar buster? It does have one very clear
mechanism and roll it coats these sweet receptors which you tend to find in the
the back of the tongue and the palate after swallowing or swishing around some
of that Gymnema powder you pretty much lose the taste for sweet. Now somebody I
was just reading comments on that on that video and somebody said well
doesn’t that make things taste differently.
Sure does if it’s something that was sweet. I will tell you I have been a
sweet-a-holic my whole life and that’s not really good for an insulin resistant
person or pre-diabetic like I am. I can tell you I mean it’s been a battle as
long as I can remember at least thirty years that I know it’s been a battle
when I was a teenager just try to stay away from sweets I wish I just this past
week started trying that Gymnema and dang it helped it’s not the battle
that I’ve been fighting for 45 years. I wish I’d known about it long long ago.
Now there may be some other about biochemical or biological mechanisms
central mechanisms after it’s absorbed in terms of maybe a impacting absorption
of sweets down in the gut absorption of sweets and other places but that’s not
very clear. It doesn’t matter to me. It’s helping me impact it and get and get
away from that battle over I want something sweet you all want something
sweet okay I hope that answered your question.
I have also lost 10 pounds in them on your protocol since your channel see you
in future before I have a heart problem Well good I do look forward to seeing
you and thank you very much for sharing that. Waylynn do you think a lot of
health issues occur because people are unaware they are not hydrated properly.
You know you clearly have problems with young people like young athletes doing
two-a-days in 100 degree weather and young athlete are young people that
think that it’s not an athletic event but then they decide they want to go rim
to rim in the Grand Canyon those are places where you get tragic events with
him and dad and heatstroke and heatstroke occurs in a lot of work areas but that’s
one thing and that’s very and you’re gonna say well I’m not talking about
that I’m talking about maybe even a heart attack from being being dehydrated
there is a if you look it up on on the web you Google it you’ll see it excuse
me a lot of claims that you can get a heart attack excuse me from being
dehydrated that’s not true okay : Weyland from the Republic of Ireland to have you and I was gonna try to say
something silly about some sort of Irish grading herb but I’m not good at
anything so thank you very much for telling us
you’re from Ireland and again very glad to have you
Neal Higgins is that statin you mentioned better than Crestor. Here’s
the advantage to pitavastatin or Livalo.
The advantage is this all the other statins sort of continue to push you
down the insulin resistance diabetes highway even Crestor I when I used statin
it’s almost in the past it’s almost always been well at least for the past
two years it’s it’s usually been low-dose Crestor. So low-dose Crestor
is not going to push you that far over the past year well here’s what happened
a few years ago a new statin came out Livalo pitavastatin and it had a
major advantage not only does it not push you down that insulin resistance
highway diabetes highway it actually starts to pull you back it actually
decreases insulin resistance now haven’t used it much it came out of more than a
year ago. I didn’t use it in the beginning for two reasons. Number one, it
cost a huge amount and it had very few people that whose insurance would pay
for it or wanted to pay for it themselves when they had a perfectly
good option like crystal. The other issue was this the major reason I give statins
is not to manage LDL that’s not really the issue the issue is to decrease
inflammation inflammation is where your own and you’re taking friendly-fire your
body is attacking the immune cells in your body is attacking LDL that has
lodged in your artery wall you’ve had some a challenge to the glycocalyx
usually due to having a few hours of a blood sugar 180 or above 140 or above
and if you have a few hours that they’ve got pictures of the
glycocalyx before and after and it looks like somebody came along with a
lawnmower and just cut out major chunks of the glycocalyx. When that happens LDL
that is in your blood no matter what concentration it is it can go through
that glycocalyx and lodges in the artery wall so that’s why they always
originally thought that cholesterol was the problem because plaque is made up of
oxidized LDL lodged in the artery wall so they thought originally. Well you are
what you eat and this must be coming from the bloodstream after you eat it.
Then they found out well actually where we make far more cholesterol than we eat that started to take a chunk out of the
cholesterol fad the next thing was we we recognized that half of the people
having heart attacks have normal cholesterol values so yet another big
chunk out of the LDL theory. And I can tell you, I’ve got plenty of patients
that have FH familial hypercholesterolemia. These people have
an LDL of 250 300 350. They still still tend to not have a
problem in their early decades and still not have a problem with with events or
even inflammation until they start getting into their 50s and 60s or they
start getting obese. In other words they start getting insulin resistance. We
covered we’ve covered several folks with FH on the channel I’m blanking on her
name right now but one one lady shared with us that… oh Sue… she shared with us
that she was a big smoker she had ended up having having to have oh she had a
she had to have stents and then surgery multiple times but that was
because she was smoking she had a smoking habit in addition to
her FH her high cholesterol. She dropped her smoking, had her surgery, but then she
started gaining weight. She went from 125 to 250 and she went
about 15 years from her first event I think was in her mid 30s. Her second
event was in her 50s and again she weighed twice what she had weighed
before. So she was a great example of how the cholesterol itself is not what God
or it was when something else was added to it like cigarettes or obesity leading
to obviously insulin resistance. I think I’ve gone off down a bunny trail. Would
you consider low-dose Crestor? I’ve always used blood Oh swell for the past
couple of years that’s been 90 percent of what I’ve used Crestor has a
half-life of 17 hours so you can actually I’ve got several people on a
standard low dose crest or dosages 5 milligrams a day I’ve got plenty of
people on two and a half a day some people on two and a half or five twice a
week three times a week and I even have a few people on once a week this the
research has been done it’s it’s shown you actually do get a positive impact
even with once a week Crestor. Now can you do that with the other
statins? No, not unless the half-life is that long and it’s not that long in
most of them. James Cantor or Bart Robinson. I am now a diabetic under
control with an a1c of 5% OGTT, was never suggested and not sure if I should
ask for it now. James at some point with my folks even that are standard
diabetics I do get one every year so because they want to understand just
what kind of shape your pancreas is in what kind of shape your insulin
resistance is in Dr. Sidkey does low-dose Crestor cause
muscle aches fatigue and associated side effects you find with higher doses such
as 80 much lower much lower problem set of problems
doctor safety great question thank you amazon just turn turn 280 my Cal score
calcium score was 69 in six months I’ve gone from 185 to 137 and my wife thinks
is low enough. Is there a weight you would consider a stopping point
for most of us the low 20s in terms of BMI and you can look that up on Google
just Google BMI calculator and it’ll give you it’ll give you a section. Enter
your weight, enter your height, and it’ll automatically pop up your numbers your
BMI so for most of us target that if you’ve got as much more muscle as in his
little fat his Arnold Schwarzenegger head when he was Mr. Olympia slightly
different question and but with either of them you can use a SPECT scan but
it’s or RFM relative fat mass is technically the best thing to use but
that hasn’t caught on yet and that’s gonna be a few years before it does. If
you want to look, I’ve got several videos on BMI (body mass index) and RFM (relative
fat mass). Mr. white Tully question all cardiologists most agree that magnesium
supplements are important did you look into Dr. Carolyn Dean’s magnesium remag
it had been a game-changer for me I’m not affiliated with her I’m not
affiliated with her either and I haven’t looked at her specific one I do know
that there are several important impacts of magnesium even and here’s the thing
even I don’t know anybody that would say that the typical American is not
magnesium deficient. Magnesium has impact for both for the GI system, for mental
health. Too little magnesium tends it can cause depression
and or anxiety and even the CDC the NIH all of us would say the typical American
is magnesium deficient so take if you’re not taking magnesium if you’re not aware
of what we just talked about check it out.
Bart Robinson James hopefully Dr. Brewer will give his take on that oh I think
that was the question about should a diabetic ever get an i energy titi my
447 Degrees West my son smokes that’s just that is so frustrating I have a
personal close family member who smokes as well and when I when he started it
was like what could I be doing wrong I cannot believe this
that’s just so heartbreaking there is a major there’s a resurgence of smoking
especially in teenagers right now and it’s you know gosh it was just a few
years ago that smoking that obesity took over from smoking is the number one
cause of risk factor driving death and disability and it’s like just when we
thought we were getting our hand a handle around smoking it’s don’t go back
in the water it’s coming back it’s like jaws Neal Higgins Dr. Brewer what is
your exercise routine so I live in a condo complex which has a wonderful walk
it’s about a mile mount it was several different walks here one of them is one
mile another one is about three-quarters of a mile and what I tend to do my kids
laugh at me because they left I get paid to talk I’ll tend to put my my
headphones on long phone calls and walk so I get a lot of walking usually
several miles a day I stand you may have noticed that I’m
not sitting I don’t sit on any of my presentations because sitting is the new
new smoking its sittings bad for you so I do those two things here’s what I do
twice a week I’ll have a sessions where I do high intensity intervals and
resistance training the high intensity interval is about our sessions are about
half an hour I start it’s mostly treadmill I start off on a we don’t know
exactly what level these inclines are but it’s a treadmill at a marking of one
half and then eight and a half miles per hour and five minutes then a couple of
minutes of slow and then the next five intervals will be at ten miles per hour
that’s a six-minute mile pace but only for one minute not a whole mile and then
one minute of slow so 10 miles per hour on usually a half the the first level of
incline and then back after I do those five then I’ll do a couple of two to
three minutes at a level about five to six times higher it’s a significant
incline so I’m getting more and more incline in the insulin I mean in the
high intensity interval the other thing I do is a lot of resistance training if
I’ve got a couple of videos on sarcopenia loss of muscles and ways to
prevent that and one of them if you look at a couple of the guys that have held a
lot of World Records in terms of both bodybuilding like Arnold Schwarzenegger
or lifting multiples of your weight that’s a fellow named Richard “The Ant”
Hawthorne I’ve got a couple of videos on those guys and and they both use a thing
called the Austrian as in Vienna Austria the Austrian volume method most people
think that you do a set of ten or eight or ten for your for your upper body and
sets of twelve for your lower body and maybe do three sets both of these guys
say no that’s not it at all you go for about a hundred reps total the first 40
reps it’s light enough to where you feel like I hope people aren’t looking at me
because I’m lifting some so little weight and you feel like you’re being
silly but what you’re doing is depleting
glycogen in your muscles as you do that then the next 40 are you know it’s not
like you’re really pushing it out but you feel it and then the last 20 you do
as much as you can so and I do squats bench press on a lot of Cybex machine
type work so that’s the workout I do that twice a week and then I do a ton of
walking what do I think of wellbutrin wellbutrin has been a very very helpful
tool in terms of smoking cessation doctor farm c2e cheers also James if
you’re a type 2 and a1c should be four point five to five yep that’s the goal
doctor farm C D currently taking metformin er 500 twice a day and I was
in pic point five milligrams a week Richard Morris hi Dr. Brewer would a
person with NAFLD produced diabetic symptoms like a high a1c or would it be
the reverse of a high one C causing NAFLD because I believe I have fatty
liver but don’t know what came first fatty liver is one of the I’ve got
several videos on fatty liver it’s one of those things that’s very very much
related to this diabetes diabetes and insulin resistance and obesity epidemic
all the things that you do for diabetes and insulin resistance are things that
help with fatty liver actually there’s some interesting statistic was it liver
cancer has become as a big I don’t know it became like one
of the top cancers or cancer deaths among women or men I don’t know again I
can’t even remember the fact for you to fact-check male its the meetings getting
long in the tooth guys especially if we go over an hour folks tend to not want
to take a look at it if in the reviews and replace. Thank you very much for your
interest. Check out and be keep your eyes open be thinking about the webinars.
It’s a great way to start getting a handle on where you are yourself. Thank
you.

9 Replies to “Insulin Resistance of the Brain (T3DM) and Our New Webinar Pilot”

  1. Hi Dr. Brewer my name is Josh Lee I'm 35 years old and I live in the west Indies Trinidad and Tobago. I'm interested in your help addressing an issue I have with my left bicep which started twitching about 1 week ago. This would be happening periodically about 3 to 5 times per day. There is no pain or weakness in the arm and from the little information I gathered from the Internet I think the cause may be the depletion of my electrolytes. I'm not quite sure however, and so, any help you can offer me in identifying my problem and how to successfully address it would be greatly appreciated. Thank you.

  2. I just send a lot of my collegues a link starting at 20 min … to get them a warning . Working irrigular hours hightens the risk of inflammation because eating is irregular and intermittend …addicted to the sugar spike . Thanks for the Gymnema tip …. if it brings the sugar craving down than that will be a battle less.BTW I have started the 12 AM O'clock eat and to 05 PM max … its doable.

  3. This is an outstanding idea. Let me make a suggestion if you put together one YouTube video of what labs you are recommending many people.will find their family physicians willing to order these tests. Be very specific and the reason behind it.
    My doctor has been willing to even offer the Kraft survey because of the information you provided and is willing to order a CIMT. If you specify the needed labs, I can get the tests I just can't interpret the results.

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